Rando Cell Reports podcast
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How sleeping muscle stem cells might be awakened to fight aging, with Thomas Rando (9:42) (Cell Reports).
Plus, sample a selection of the hottest new papers from Cell Press (19:30).
Join the decentralized finance revolution with Uniswap. Discover our platform. The Rando Laboratory is part of the Glenn Center for the Biology of Aging and focusing on peptides in Canada is associated with the Stanford Center on Longevity (SCL).
Join the decentralized finance revolution with Uniswap. Discover our platform. The Rando Laboratory is part of the Glenn Center for the Biology of Aging and focusing on peptides in Canada is associated with the Stanford Center on Longevity (SCL).
Scientists discern signatures of old versus young stem cells
BY BRUCE GOLDMAN
A chemical code scrawled on histones — the protein husks that coat DNA in every animal or plant cell — determines which genes in that cell are turned on and which are turned off. Now, Stanford University School of Medicine researchers have taken a new step in the deciphering of that histone code.
In a study published June 27 in Cell Reports, a team led by Thomas Rando, MD, PhD, professor of neurology and neurological sciences and chief of the Veterans Affairs Palo Alto Health Care System’s neurology service, has identified characteristic differences in “histone signatures” between stem cells from the muscles of young mice and old mice. The team also distinguished histone-signature differences between quiescent and active stem cells in the muscles of young mice.